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Deon Cole is originally from the south side of Chicago. He is one of the most requested headlining comedians in the club and college circuit nation wide. He is also a successful actor, having appeared in MTV's Short Circuitz and Wild N' Out with Nick Cannon, as well as Barbershop 1 and 2. As a standup, he has been featured on The Tonight Show with Conan O'Brien, Comedy Central's Laffapalooza, HBO's Def Comedy Jam, BET's Comic View, NBC's Showtime at the Apollo, BBC's The World Stands Up, and STARZ' Martin Lawrence's First Amendment. Deon also had his own half-hour special on Comedy Central which premiered in 2007.

After Deon's standup appearance on The Tonight Show, he was offered a job as a staff writer for the show and has since made multiple appearances as a commentator and sketch performer on the show. TV Guide declared, “A Star is Born” after Deon's commentary pieces kept growing as a bit on the show. He is currently a featured act on Conan O'Brien's THE LEGALLY PROHIBITED FROM BEING FUNNY ON TELEVISION TOUR.

Deon has been a featured comic in the HBO US Comedy Arts Festival in Aspen and the CanWest Comedy Fest in Vancouver. He was a finalist in NBC's Stand-Up for Diversity Showcase and he won BET's Robin Harris Award for most original comic. He has been part of several tours including the Cole-Cola World European Tour for the Troops (Germany, Amsterdam, Belgium, Japan, & Korea), the BET Comedy Tour, the Def Jam Tour, the Budweiser Superfest R. Kelly Tour and the Mary J. Blige Tour. Deon's charismatic personality and original style make him one of the most popular performers in the comedy scene today.